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The journey from Milton Keynes Central to Manchester Piccadilly on the fastest train in 2 hours 25 minutes, usually 2 hours 49 minutes. Each day, 32 trains leave from Milton Keynes Central, starting at 06:25 and ending at 21:40. Get real-time updates on train schedules, delays, and cancellations. Save time, effort, and money with TrainPal.
| Departs | Arrives | Operator | ||
|---|---|---|---|---|
08:40 Milton Keynes Central | 2 hours 25 minutes, 1 change | 11:05 Manchester Piccadilly | Avanti West Coast | Find tickets |
08:55 Milton Keynes Central | 2 hours 49 minutes, 2 change | 11:44 Manchester Piccadilly | Avanti West Coast | Find tickets |
09:40 Milton Keynes Central | 2 hours 25 minutes, 1 change | 12:05 Manchester Piccadilly | Avanti West Coast | Find tickets |
09:55 Milton Keynes Central | 2 hours 49 minutes, 2 change | 12:44 Manchester Piccadilly | Avanti West Coast | Find tickets |
10:40 Milton Keynes Central | 2 hours 25 minutes, 1 change | 13:05 Manchester Piccadilly | Avanti West Coast | Find tickets |
Plan your journey from Milton Keynes Central to Manchester Piccadilly with ease. Explore the first and last train times, departure and arrival stations, distance, journey time, and price options to make the most of your trip.
Travel from Milton Keynes Central to Manchester Piccadilly in just 1 hour 41 minutes on direct Avanti West Coast services.
On one efficient, direct train, you can travel from Milton Keynes to Manchester, with a premium travel experience and picturesque views of Northamptonshire and Staffordshire countryside from your window. When booking in advance with TrainPal, you can buy cheap train tickets from Milton Keynes to Manchester using railcard discounts, split tickets and advance fares.
Avanti West Coast runs long-distance trains around the West of England, with fast services connecting major cities such as Manchester, Liverpool, London, Crewe, Chester and Wigan.
To the west of Milton Keynes town centre, Milton Keynes Central is a well-connected Buckinghamshire station that offers passengers routes to get to some of England’s top destinations.
With waiting rooms and seating areas, Milton Keynes Central is a comfortable location from which to start your journey. Reaching the station is easy, whether by local bus or taxi, both of which serve the station. The station also has plentiful bike storage facilities, as well as a drop-off point for cycle hires operated by Santander Cycles outside the front of the station.
Milton Keynes Station is part of popular routes to places like London Euston, Liverpool Lime Street, Birmingham New Street, and Manchester Piccadilly. Operated by London Northwestern Railway, the other major operators with a presence at the station are Avanti West Coast and West Midlands Trains.
From Milton Keynes Central to Manchester Piccadilly, your Avanti West Coast service will stop at Rugby, Stoke-On-Trent, Macclesfield, and Stockport before arriving in Manchester. Stops may vary on different services, depending on when you make your journey.
Manchester Piccadilly is a convenient terminus for your journey from Milton Keynes to Manchester. A major northern hub, Manchester Piccadilly is a well-connected station located to the south of the city.
Within a few minutes’ walk, you’ll be able to reach attractions like Piccadilly Gardens, while city centre shopping, bars, and restaurants are just a little further. The station is conveniently connected to local bus routes, as well as through the Manchester 'Metrolink' tram network.
Manchester Piccadilly transports passengers around the UK, with destinations as far afield as Norwich, Llandudno, Stoke-On-Trent, Sheffield, Windermere, Liverpool Lime Street, and London Euston. The station’s major operators are TransPennine Express, Avanti West Coast, Transport for Wales, Northern, and East Midlands Railway.
Onboard services from Milton Keynes Central to Manchester Piccadilly, you can choose between three different train classes:
*Information is subject to change. Please check the latest train timetable before your trip.
Taking the train from Milton Keynes Central to Manchester Piccadilly is both efficient and enjoyable, offering scenic views and comfort. With frequent departures from Milton Keynes Central, you can arrive at Manchester Piccadilly in just 2 hours 25 minutes, making it a quick and convenient option for travelling between these two places.

The quickest train journey from Milton Keynes Central to Manchester Piccadilly takes 2 hours 25 minutes . Utilise our Train Journey Planner to locate direct trains, minimise transfers, and compare travel times across various routes. Discover the most efficient way to travel with fewer stops for a smooth and seamless journey.
No, you will need to transfer when travelling from Milton Keynes Central to Manchester Piccadilly. TrainPal Train Journey Planner will assist you in finding the best train route. Enter the origin or destination places and other relevant details, then click "Search" to find the most suitable route.

While Milton Keynes Central to Manchester Piccadilly trains are usually on time, delays or disruptions may occur due to weather, strikes, and other factors. Finding a train timetable for your trip from Milton Keynes Central to Manchester Piccadilly is easy with Train Journey Planner. Simply enter your departure and arrival stations to get a detailed schedule of available trains. Input your travel details to discover the best routes, connections, and train times.
Usually, you need to arrive at a station at least 15-20 minutes ahead of time. However, consider the station's size and your familiarity with it. If the station is large and you are not familiar with it, leaving home as early as possible is the best choice. This can reduce your stress and ensure a relaxing journey.
Yes, most trains on the route from Milton Keynes Central to Manchester Piccadilly are equipped with Wi-Fi. Passengers can also enjoy complimentary food, drinks, and power sockets for a more comfortable journey. Please note that the availability of these services can vary depending on the train company
Check our Train Journey Planner, which provides detailed information about transfers to ensure your journey is uninterrupted, saving you time and effort, and allowing you to get a full rest for travelling.

Checking train delays and cancellations in the UK is simple. Utilise the TrainPal mobile app for real-time information. We offer live updates, including live train status and notifications of any train strikes.
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