Firenze S. M. Novella to Rome Termini Trains from €13.08

Departure station: Departing from Firenze Santa Maria Novella

If you're travelling from Firenze S. M. Novella to Rome Termini by train, you'll depart from Firenze Santa Maria Novella, Florence's main railway station. Located on the edge of the historic centre, it's within easy walking distance of many of the city's best-known attractions, making it a convenient departure point whether you're staying in Florence or visiting for the day.

From Florence's historic centre, Firenze Santa Maria Novella is around a 10 to 15-minute walk from Piazza del Duomo and can also be reached by local buses and trams serving the station, keeping things simple for travellers. Taxis are readily available throughout the city too, making it easy to reach the station if you're travelling with luggage or staying further afield.

The station is modern and easy to navigate, with plenty of cafés, restaurants, shops and waiting areas. If you've checked out of your accommodation before your train, you can use the Deposito Bagagli left-luggage facility to explore Florence for a little longer before departing. High-speed services are clearly displayed on the departure boards, but it's still worth arriving around 20 minutes before departure to locate your platform.

Arrival station: Arriving at Rome Termini

You'll arrive at Rome Termini, Italy's largest railway station and the main gateway to the capital. From here, it's easy to continue your journey using Metro Lines A and B, with Line A providing direct access to the Vatican, the Spanish Steps and Piazza del Popolo, while Line B serves landmarks including the Colosseum, Circus Maximus and the EUR district. Local buses, taxis and regional rail services are also readily available for travellers. If your hotel is in the historic centre, you may find it's quicker to use the metro than a taxi during the busiest parts of the day, but it’s worth checking first.

Many of Rome's most popular attractions are within easy reach of the station. The Colosseum is only a couple of metro stops away, while the Trevi Fountain and Spanish Steps can be reached on foot or by public transport. Official taxi ranks are located outside the station, and it's always best to use these rather than accept offers from drivers inside the terminal.

Florence to Rome is one of Europe's great high-speed rail journeys, with both Frecciarossa and Italo linking the two city centres in around 90 minutes. Both Trenitalia's Frecciarossa services and Italo's modern trains operate frequent direct departures, allowing you to travel between the two city centres in around 90 minutes without the hassle of airport transfers.

Frecciarossa high-speed trains

• Avg. duration: From 1 hour 31 minutes
• Departure station: Firenze Santa Maria Novella
• Best for: Frequent departures, excellent onward connections and flexible ticket options.
• Onboard perks: Standard, Premium, Business and Executive Class, free WiFi, power sockets, air conditioning and the FrecciaBistrò café on many services.
• Worth Knowing: Frecciarossa trains are ideal if you're connecting with other Trenitalia services elsewhere in Italy or want a wide choice of departure times throughout the day.

Italo high-speed trains

• Avg. duration: From 1 hour 30 minutes
• Departure station: Firenze Santa Maria Novella
• Best for: Competitive advance fares, comfortable seating and fast city centre to city centre travel.
• Onboard perks: Free WiFi, spacious luggage storage, reclining seats and Smart, Prima and Club Executive travel classes.
• Worth Knowing: Italo is often an excellent choice if you book early, with competitive fares and modern trains offering a smooth, comfortable journey to Rome.

Regionale and Regionale Veloce 

• Avg. duration: From 3 hours 52 minutes
• Departure station: Firenze Santa Maria Novella
• Best for: Lower-cost travel, direct regional services and travellers who aren't in a hurry.
• Onboard perks: Comfortable seating, luggage storage and air-conditioned coaches on most services.
• Worth Knowing: While much slower than Frecciarossa and Italo services, some Regionale Veloce trains do run directly between Florence and Rome, making them a good-value option if you'd prefer to avoid changing trains and don't mind a longer journey.

• Book as early as possible: This is one of Italy's busiest high-speed rail routes, so advance booking often secures the lowest fares, particularly during weekends, holidays and the summer season.
• Train or plane? High-speed rail is often the more convenient option. You'll travel directly between Florence and central Rome, avoiding airport transfers and lengthy security queues.
• Stay up to date: Although high-speed services are generally very reliable, platform changes can happen. When you book your train tickets from Firenze S. M. Novella to Rome Termini with TrainPal, you can check live train updates before you travel.
• Enjoy the journey: The route passes through the rolling countryside of Tuscany before continuing into Lazio. A window seat is well worth choosing if you're travelling during daylight hours.
• Book with TrainPal: TrainPal allows you to compare Firenze S. M. Novella to Rome Termini train tickets across both Trenitalia and Italo, helping you find the best fare while keeping your tickets and live journey information in one convenient place.